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Below is the 2012 NFL schedule for the Rams
| WK | DATE | OPPONENT | TIME (ET) |
| 1 | Sun, Sep 9 | at Detroit | 1:00 PM |
| 2 | Sun, Sep 16 | Washington | 4:05 PM |
| 3 | Sun, Sep 23 | at Chicago | 1:00 PM |
| 4 | Sun, Sep 30 | Seattle | 1:00 PM |
| 5 | Thu, Oct 4 | Arizona | 8:20 PM |
| 6 | Sun, Oct 14 | at Miami | 1:00 PM |
| 7 | Sun, Oct 21 | Green Bay | 1:00 PM |
| 8 | Sun, Oct 28 | New England | 1:00 PM |
| 10 | Sun, Nov 11 | at San Francisco | 4:15 PM |
| 11 | Sun, Nov 18 | NY Jets | 1:00 PM |
| 12 | Sun, Nov 25 | at Arizona | 4:15 PM |
| 13 | Sun, Dec 2 | San Francisco | 1:00 PM |
| 14 | Sun, Dec 9 | at Buffalo | 1:00 PM |
| 15 | Sun, Dec 16 | Minnesota | 1:00 PM |
| 16 | Sun, Dec 23 | at Tampa Bay | 1:00 PM |
| 17 | Sun, Dec 30 | at Seattle | 4:15 PM |
